AirKit: A Citizen-Sensing Toolkit for Monitoring Air Quality.

Increasing urbanisation and a better understanding of the negative health effects of air pollution have accelerated the use of Internet of Things (IoT)-based air quality sensors. Low-cost and low-power sensors are now readily available and commonly deployed by individuals and community groups. However, there are a wide range of such IoT devices in circulation that differently focus on problems of sensor validation, data reliability, or accessibility. In this paper, we present AirKit, which was developed as an integrated and open source "social IoT technology". AirKit enables a comprehensive approach to citizen-sensing air quality through several integrated components: (1) the Dustbox 2.0, a particulate matter sensor; (2) Airsift, a data analysis platform; (3) a reliable and automatic remote firmware update system; (4) a "Data Stories" method and tool for communicating citizen data; and (5) an AirKit logbook that provides a guide for designing and running air quality projects, along with instructions for building and using AirKit components. Developed as a social technology toolkit to foster open processes of research co-creation and environmental action, Airkit has the potential to generate expanded engagements with IoT and air quality by improving the accuracy, legibility and use of sensors, data analysis and data communication.This research was supported by the European Research Council under the European Union’s Seventh Framework Programme (FP/2007–2013)/ERC Grant Agreement n. 313347, “Citizen Sensing and Environmental Practice: Assessing Participatory Engagements with Environments through Sensor Technologies”, and from the European Research Council under the European Union’s Horizon 2020 research and innovation programme (ERC Grant Agreement n. 779921), “AirKit: Citizen Sense Air Monitoring Kit”. The University of Cambridge provided additional support through the ESRC Impact Acceleration Account (2020) for enabling impact

Portfolio of original compositions with written commentary

Sound propagates through space as a series of vibrations which are mediated, perceived and interpreted by the listening body. Whilst the body receives the physicality of sound, we predominantly focus on our listening experience through audition. In this work, I propose approaches to employing haptics, or vibration technologies, as a mechanism through which we can extend our experience of sound across the body and achieve a greater control of its physical presence. I will discuss ideas pertaining to sound as a physical and embodied practice, and the ways that I have explored this through developing conceptual systems relating sonic and physical materials. During the production of this work, themes of embodiment, mediation and immersion emerge which are unpacked through this commentary. Many of the works in this portfolio employ an audio and a haptic element that controls sound and vibration in synchrony, with the physical element rendered on bespoke haptic displays. A latter work explores the development of and performances with an algorithmic language for choreography. In this commentary, I reflect on each individual piece, documenting the process of making and subsequent outcomes to my creative thinking. Overall this project is underlined by a reflexive methodology where each new piece of practice influences the formation of the next—revealing new opportunities, concepts and technological approaches. I do not present a framework for the development of audio-haptic works, instead, I document and reflect on the processes through which my own practice has found connections, tensions and opportunities between the two forms. I conclude that whilst the inclusion of haptics heavily mediates and reconfigures the experience of listening, it can function as an immersive addition to sound that provokes presence, aura and tangibility in abstraction

Proceedings of the 1st International Conference on Live Coding

Open Access peer reviewed papers on live coding published at the 1st International Conference on Live Coding (ICLC) in Leeds

Haptics for the development of fundamental rhythm skills, including multi-limb coordination

This chapter considers the use of haptics for learning fundamental rhythm skills, including skills that depend on multi-limb coordination. Different sensory modalities have different strengths and weaknesses for the development of skills related to rhythm. For example, vision has low temporal resolution and performs poorly for tracking rhythms in real-time, whereas hearing is highly accurate. However, in the case of multi-limbed rhythms, neither hearing nor sight are particularly well suited to communicating exactly which limb does what and when, or how the limbs coordinate. By contrast, haptics can work especially well in this area, by applying haptic signals independently to each limb. We review relevant theories, including embodied interaction and biological entrainment. We present a range of applications of the Haptic Bracelets, which are computer-controlled wireless vibrotactile devices, one attached to each wrist and ankle. Haptic pulses are used to guide users in playing rhythmic patterns that require multi-limb coordination. One immediate aim of the system is to support the development of practical rhythm skills and multi-limb coordination. A longer-term goal is to aid the development of a wider range of fundamental rhythm skills including recognising, identifying, memorising, retaining, analysing, reproducing, coordinating, modifying and creating rhythms – particularly multi-stream (i.e. polyphonic) rhythmic sequences. Empirical results are presented. We reflect on related work, and discuss design issues for using haptics to support rhythm skills. Skills of this kind are essential not just to drummers and percussionists but also to keyboards players, and more generally to all musicians who need a firm grasp of rhythm

Progress toward curing HIV infection with hematopoietic cell transplantation.

HIV-1 infection afflicts more than 35 million people worldwide, according to 2014 estimates from the World Health Organization. For those individuals who have access to antiretroviral therapy, these drugs can effectively suppress, but not cure, HIV-1 infection. Indeed, the only documented case for an HIV/AIDS cure was a patient with HIV-1 and acute myeloid leukemia who received allogeneic hematopoietic cell transplantation (HCT) from a graft that carried the HIV-resistant CCR5-∆32/∆32 mutation. Other attempts to establish a cure for HIV/AIDS using HCT in patients with HIV-1 and malignancy have yielded mixed results, as encouraging evidence for virus eradication in a few cases has been offset by poor clinical outcomes due to the underlying cancer or other complications. Such clinical strategies have relied on HIV-resistant hematopoietic stem and progenitor cells that harbor the natural CCR5-∆32/∆32 mutation or that have been genetically modified for HIV-resistance. Nevertheless, HCT with HIV-resistant cord blood remains a promising option, particularly with inventories of CCR5-∆32/∆32 units or with genetically modified, human leukocyte antigen-matched cord blood

Do as we say and as we do: The interplay of descriptive and injunctive group norms in the attitude-behaviour relationship

This is the author's post-print version of an article whose final and definitive form has been published in the British Journal of Social Psychology. Reproduced with permission from the British Journal of Social Psychology © The British Psychological Society 2008. The definitve version is available at: http://www.bpsjournals.co.uk/journals/bjsp/Past research on the social identity approach to attitude-behaviour relations has operationalized group norms as a mixture of both descriptive information (i.e. what most people do themselves) and injunctive information (i.e. what most people approve of). Two experiments (Study 1=185 participants; Study 2=238 participants) were conducted to tease apart the relative effects of descriptive and injunctive group norms. In both studies, university students' attitudes towards current campus issues were obtained, the descriptive and injunctive group norms were manipulated, and participants' post-manipulation attitudes, behavioural willingness, and behaviour were assessed. Study 2 also examined the role of norm source (i.e. in-group vs. out-group injunctive and descriptive norms). In both studies, the injunctive and descriptive in-group norms interacted significantly to influence attitudes, behavioural willingness, and behaviour. Study 2 revealed that out-group norms were largely ineffective. The research illustrates that in-groups interactively influence decisions, not only by what they say, but also by what they do, and asserts the value of considering the interaction of descriptive and injunctive norms in accounts of normative influence

Uncertainty and the influence of group norms in the attitude–behaviour relationship

This is the author's post-print version of an article whose final and definitive form has been published in the British Journal of Social Psychology. Reproduced with permission from the British Journal of Social Psychology © The British Psychological Society 2007. The definitve version is available at: http://www.bpsjournals.co.uk/journals/bjsp/Two studies were conducted to examine the impact of subjective uncertainty on conformity to group norms in the attitude–behaviour context. In both studies, subjective uncertainty was manipulated using a deliberative mindset manipulation (McGregor, Zanna, Holmes, & Spencer, 2001). In Study 1 (N=106), participants were exposed to either an attitude-congruent or an attitude-incongruent in-group norm. In Study 2 (N=83), participants were exposed to either a congruent, incongruent, or an ambiguous in-group norm. Ranges of attitude–behaviour outcomes, including attitude-intention consistency and change in attitude-certainty, were assessed. In both studies, levels of group-normative behaviour varied as a function of uncertainty condition. In Study 1, conformity to group norms, as evidenced by variations in the level of attitude-intention consistency, was observed only in the high uncertainty condition. In Study 2, exposure to an ambiguous norm had different effects for those in the low and the high uncertainty conditions. In the low uncertainty condition, greatest conformity was observed in the attitude-congruent norm condition compared with an attitude-congruent or ambiguous norm. In contrast, individuals in the high uncertainty condition displayed greatest conformity when exposed to either an attitude-congruent or an ambiguous in-group norm. The implications of these results for the role of subjective uncertainty in social influence processes are discussed

Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors

Background: Limits on the frequency of whole blood donation exist primarily to safeguard donor health. However, there is substantial variation across blood services in the maximum frequency of donations allowed. We compared standard practice in the UK with shorter inter-donation intervals used in other countries. Methods: In this parallel group, pragmatic, randomised trial, we recruited whole blood donors aged 18 years or older from 25 centres across England, UK. By use of a computer-based algorithm, men were randomly assigned (1:1:1) to 12-week (standard) versus 10-week versus 8-week inter-donation intervals, and women were randomly assigned (1:1:1) to 16-week (standard) versus 14-week versus 12-week intervals. Participants were not masked to their allocated intervention group. The primary outcome was the number of donations over 2 years. Secondary outcomes related to safety were quality of life, symptoms potentially related to donation, physical activity, cognitive function, haemoglobin and ferritin concentrations, and deferrals because of low haemoglobin. This trial is registered with ISRCTN, number ISRCTN24760606, and is ongoing but no longer recruiting participants. Findings: 45 263 whole blood donors (22 466 men, 22 797 women) were recruited between June 11, 2012, and June 15, 2014. Data were analysed for 45 042 (99·5%) participants. Men were randomly assigned to the 12-week (n=7452) versus 10-week (n=7449) versus 8-week (n=7456) groups; and women to the 16-week (n=7550) versus 14-week (n=7567) versus 12-week (n=7568) groups. In men, compared with the 12-week group, the mean amount of blood collected per donor over 2 years increased by 1·69 units (95% CI 1·59–1·80; approximately 795 mL) in the 8-week group and by 0·79 units (0·69–0·88; approximately 370 mL) in the 10-week group (p<0·0001 for both). In women, compared with the 16-week group, it increased by 0·84 units (95% CI 0·76–0·91; approximately 395 mL) in the 12-week group and by 0·46 units (0·39–0·53; approximately 215 mL) in the 14-week group (p<0·0001 for both). No significant differences were observed in quality of life, physical activity, or cognitive function across randomised groups. However, more frequent donation resulted in more donation-related symptoms (eg, tiredness, breathlessness, feeling faint, dizziness, and restless legs, especially among men [for all listed symptoms]), lower mean haemoglobin and ferritin concentrations, and more deferrals for low haemoglobin (p<0·0001 for each) than those observed in the standard frequency groups. Interpretation: Over 2 years, more frequent donation than is standard practice in the UK collected substantially more blood without having a major effect on donors' quality of life, physical activity, or cognitive function, but resulted in more donation-related symptoms, deferrals, and iron deficiency. Funding: NHS Blood and Transplant, National Institute for Health Research, UK Medical Research Council, and British Heart Foundation

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

Background Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy

Supporting genetics in primary care: investigating how theory can inform professional education

Evidence indicates that many barriers exist to the integration of genetic case finding into primary care. We conducted an exploratory study of the determinants of three specific behaviours related to using breast cancer genetics referral guidelines effectively: 'taking a family history', 'making a risk assessment', and 'making a referral decision'. We developed vignettes of primary care consultations with hypothetical patients, representing a wide range of genetic risk for which different referral decisions would be appropriate. We used the Theory of Planned Behavior to develop a survey instrument to capture data on behavioural intention and its predictors (attitude, subjective norm, and perceived behavioural control) for each of the three behaviours and mailed it to a sample of Canadian family physicians. We used correlation and regression analyses to explore the relationships between predictor and dependent variables. The response rate was 96/125 (77%). The predictor variables explained 38-83% of the variance in intention across the three behaviours. Family physicians' intentions were lower for 'making a risk assessment' (perceived as the most difficult) than for the other two behaviours. We illustrate how understanding psychological factors salient to behaviour can be used to tailor professional educational interventions; for example, considering the approach of behavioural rehearsal to improve confidence in skills (perceived behavioural control), or vicarious reinforcement as where participants are sceptical that genetics is consistent with their role (subjective norm)